MYST1 蛋白
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北京 101111
Quick Overview for MYST1 蛋白 (ABIN7939229)
抗原
See all MYST1 (KAT8) 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant KAT8 / MYST1 protein
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产品特性
- KAT8 (Lysine Acetyltransferase 8), also called as MYST1 or HMOF, is a histone acetyltransferase which may be involved in transcriptional activation. It may influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. KAT8 can also acetylate TP53 / p53 at 'Lys-120'. Diseases associated with KAT8 include Atrial Septal Defect 4. Among its related pathways are Chromatin Regulation / Acetylation and Chromatin organization.
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K(lysine) Acetyltransferase 8 (KAT8) (AA 1-467) protein (GST tag)
KAT8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant KAT8 / MYST1 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
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别名
- KAT8 & MYST1
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背景
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Protein Background: KAT8 (Lysine Acetyltransferase 8), also called as MYST1 or HMOF, is a histone acetyltransferase which may be involved in transcriptional activation. It may influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. KAT8 can also acetylate TP53 / p53 at 'Lys-120'. Diseases associated with KAT8 include Atrial Septal Defect 4. Among its related pathways are Chromatin Regulation / Acetylation and Chromatin organization.
Short Description: Full length of Recombinant KAT8 / MYST1 protein (accession number NP_115564.2) was expressed in a baculovirus expression system and contains an N-terminal FLAG tag. The molecular weight of the protein is 53.7 kDa.
Aliases: MOF, Lysine Acetyltransferase 8
抗原
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