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FRK Protein (AA 208-505)

This Recombinant FRK protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7938852
发货至: 中国
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Quick Overview for FRK Protein (AA 208-505) (ABIN7938852)

抗原

See all FRK 蛋白
FRK (Fyn-Related Kinase (FRK))

蛋白类型

Recombinant

宿主

  • 11
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资源

  • 3
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Baculovirus infected Insect Cells

应用范围

Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)
  • 产品特性

    AA 208-505

    原理

    Recombinant FRK (208-505) protein
  • 想要此Protein的其他选项吗?

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    表达系统
    Conjugate
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant FRK (208-505) protein is supplied in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    FRK (Fyn-Related Kinase (FRK))

    别名

    FRK

    背景

    Protein Background: FRK is a non-receptor tyrosine-protein kinase that negatively regulates cell proliferation and positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth and may function as a tumor suppressor. Diseases associated with FRK include Co-Trimoxazole Allergy and Osseous Heteroplasia, Progressive.

    Short Description: Recombinant FRK (208-505) protein that includes amino acids 208-505 of human FRK protein (accession number NP_002022.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 36.5 kDa

    Aliases: Fyn-related kinase, Rak

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