eEF1A1 蛋白
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Quick Overview for eEF1A1 蛋白 (ABIN7938816)
抗原
See all eEF1A1 (EEF1A1) 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant EEF1A1 protein
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产品特性
- EEF1A1 (Eukaryotic Translation Elongation Factor 1 Alpha 1), also called as LENG7, CTCL Tumor Antigen or CCS3, is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. EEF1A1 is identified as an autoantigen in 66 % of patients with Felty syndrome. EEF1A1 can promote the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, it can form a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. It may also mediate accelerated synthesis of free thiol-containing proteins in response to HC-induced oxidative stress by homocysteine (HC).
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) (AA 1-462) protein (His tag)
custom-made EEF1A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) (AA 1-462) protein (His tag)custom-made EEF1A1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) (AA 1-462) protein (GST tag)EEF1A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) (AA 1-462) proteinEEF1A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) protein (Myc-DYKDDDDK Tag)EEF1A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant EEF1A1 protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- eEF1A1 (EEF1A1) (Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1))
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别名
- EEF1A1
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背景
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Protein Background: EEF1A1 (Eukaryotic Translation Elongation Factor 1 Alpha 1), also called as LENG7, CTCL Tumor Antigen or CCS3, is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. EEF1A1 is identified as an autoantigen in 66 % of patients with Felty syndrome. EEF1A1 can promote the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, it can form a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. It may also mediate accelerated synthesis of free thiol-containing proteins in response to HC-induced oxidative stress by homocysteine (HC).
Short Description: Recombinant EEF1A1 protein was expressed in E.coli as the full length protein (accession number NP_001393.1) with an N-terminal 6xHis Tag. The molecular weight of the protein is 53.7 kDa.
Aliases: Eukaryotic Translation Elongation Factor 1 Alpha 1
抗原
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