EMG1 蛋白
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北京 101111
Quick Overview for EMG1 蛋白 (ABIN7938792)
抗原
See all EMG1 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant EMG1 protein
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EMG1 Nucleolar Protein Homolog (EMG1) (AA 1-244) protein (His tag)
EMG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
EMG1 Nucleolar Protein Homolog (EMG1) (AA 1-244) protein (His-IF2DI Tag)EMG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
EMG1 Nucleolar Protein Homolog (EMG1) protein (Myc-DYKDDDDK Tag)EMG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant EMG1 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))
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别名
- EMG1
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背景
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Protein Background: Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) is a highly conserved nucleolar protein with an essential function in ribosome biogenesis. A mutation in the human Nep1 homolog causes Bowen-Conradi syndrome-a severe developmental disorder. Structures of Nep1 revealed a dimer with a fold similar to the SPOUT-class of RNA-methyltransferases suggesting that Nep1 acts as a methyltransferase in ribosome biogenesis. The target for this putative methyltransferase activity has not been identified yet.
Short Description: Recombinant EMG1 protein was expressed in E.coli as the full length protein (accession number NP_006322.4) with an N-terminal 6xHis tag. The molecular weight of the protein is 28.52 kDa.
Aliases: Ribosomal RNA small subunit methyltransferase NEP1
抗原
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