DDX54 蛋白
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北京 101111
Quick Overview for DDX54 蛋白 (ABIN7938756)
抗原
See all DDX54 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant DDX54 protein
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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54 (DDX54) (AA 778-881) protein (GST tag)
DDX54 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant DDX54 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- DDX54 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54 (DDX54))
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别名
- DDX54
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背景
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Protein Background: DDX54 (ATP-dependent RNA helicase DDX54) is a nucleolar DEAD-box RNA helicase that functions as a key regulator of transcription and ribosome biogenesis. It is recruited to gene promoters, including those of nuclear receptors and stress-responsive genes, where it acts as a transcriptional co-regulator to modulate their expression. Furthermore, DDX54 plays a direct role in the nucleolar stages of ribosomal RNA (rRNA) processing and maturation, which is essential for the proper assembly of ribosomes. Its activity is also implicated in the cellular stress response, where it contributes to the reorganization of nucleolar architecture and halts rRNA synthesis to conserve energy. Dysregulation of DDX54 has been associated with cancers, underscoring its importance in fundamental cell growth and proliferation pathways.
Short Description: Recombinant DDX54 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_001104792.1) with an N-terminal FLAG tag. The molecular weight of DDX54 is 99.94 kDa.
Aliases: ATP-dependent RNA helicase DDX54, DP97, DEAD-Box Helicase 54
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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