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CIAPIN1 蛋白

This Recombinant CIAPIN1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7938746
发货至: 中国
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Quick Overview for CIAPIN1 蛋白 (ABIN7938746)

抗原

See all CIAPIN1 蛋白
CIAPIN1 (Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant CIAPIN1 protein
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant CIAPIN1 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    CIAPIN1 (Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1))

    别名

    CIAPIN1

    背景

    Protein Background: CIAPIN1 (Cytokine-induced apoptosis inhibitor 1,also known as Anamorsin or Fe-S cluster assembly protein DRE2 homolog) is a Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 . NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity).Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

    Short Description: Recombinant CIAPIN1 protein was expressed in E.coli as the full length protein (accession number NP_064709.2) with an N-terminal 6xHis tag. The molecular weight of the protein is 35.38 kDa.

    Aliases: Anamorsin, DRE2, cytokine induced apoptosis inhibitor 1

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