CARM1 Protein (full length)
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北京 101111
Quick Overview for CARM1 Protein (full length) (ABIN7938720)
抗原
See all CARM1 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- full length
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原理
- Recombinant PRMT4 (CARM1) protein
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产品特性
- Recombinant human PRMT4 (CARM1) was expressed in a baculovirus expression system as the full-length protein (accession number NP_954592.1) with an N-terminal Flag tag. The molecular weight of the protein is 66.8 kDa. It is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Full length recombinant PRMT4 (CARM1) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100 and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- PRMT4
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背景
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Protein Background: PRMT4 (CARM1) (Coactivator-associated arginine methyltransferase 1 or Carm1) is a protein arginine N-methyltransferase that catalyzes the mono- and asymmetric dimethylation of arginine residues in its substrate proteins. It serves as a coactivator of transcription and also plays a role in nuclear receptors. PRMT4 (CARM1) methylates histone H3 at Arg2, Arg17 and Arg26, it also methylates a number of non-histone substrates involved in the regulation and mechanism of gene expression.
Short Description: Recombinant human PRMT4 (CARM1) was expressed in a baculovirus expression system as the full length protein (accession number NP_954592.1) with an N-terminal Flag tag. The molecular weight of the protein is 66.8 kDa.
Aliases: Coactivator Associated Arginine Methyltransferase 1, Protein Arginine N-Methyltransferase 4
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分子量
- 66.8 kDa
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NCBI登录号
- NP_954592
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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