CHD1L 蛋白
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北京 101111
Quick Overview for CHD1L 蛋白 (ABIN7938709)
抗原
See all CHD1L 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant CHD1L protein
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Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L) protein (Myc-DYKDDDDK Tag)
CHD1L 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant CHD1L protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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别名
- CHD1L
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背景
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Protein Background: CHD1L is a ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage. Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage. Poly-ADP-ribose-binding activates the ATP-dependent chromatin remodeler activity, thereby regulating chromatin during DNA repair. Catalyzes nucleosome sliding away from DNA breaks in an ATP dependent manner. Chromatin remodeling activity promotes PARP2 removal from chromatin.
Short Description: Recombinant CHD1L protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_004275.4) with an N-terminal FLAG tag. The molecular weight of CHD1L is 102.27 kDa.
Aliases: ALC1, Amplified In Liver Cancer Protein 1, CHDL
抗原
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