CDK2/CyclinA2 (Complex) 蛋白
Our Local Distributor
北京 101111
Quick Overview for CDK2/CyclinA2 (Complex) 蛋白 (ABIN7938689)
抗原
蛋白类型
宿主
资源
应用范围
-
-
产品特性
- Complex
-
原理
- Recombinant CDK2 / Cyclin A2 Complex
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Recombinant CDK2 / Cyclin A2 Complex is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
储存条件
- -80 °C
-
储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- CDK2/CyclinA2
-
别名
- CDK2 & Cyclin A2
-
背景
-
Protein Background: CDK2 is a serine/threonine-protein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. CDK2 / Cyclin A2 complex phosphorylate proteins like pocket proteins (Rb, p107, p130) and proteins involved in DNA synthesis, thereby driving S-phase progression. In line with its role in regulating S-phase and as a typical E2F target gene, cyclin A2 expression is induced upon entry into S-phase, persists through the S- and G2 phases, and is degraded upon entry into mitosis.
Short Description: Recombinant CDK2 / Cyclin A2 Complex that includes full length human CDK2 protein (accession number NP_001789.2) with an C-terminal His tag and full length human Cyclin A2 protein (accession number NP_001228.2) with an C-terminal FLAG tag was expressed in Hi5 cells. The molecular weights of CDK2 and Cyclin A2 are 35.57 kDa and 50.24 kDa, respectively.
抗原
-
