ADAR Protein (AA 1-295)
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北京 101111
Quick Overview for ADAR Protein (AA 1-295) (ABIN7938572)
抗原
See all ADAR 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 1-295
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原理
- Recombinant ADAR1 (1-295) protein
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Adenosine Deaminase, RNA-Specific (ADAR) (AA 2-110) protein (GST tag)
ADAR 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-176) protein (His-SUMO Tag)ADAR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Adenosine Deaminase, RNA-Specific (ADAR) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)ADAR 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-176), (partial) protein (GST tag)ADAR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant ADAR1 (1-295) protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- ADAR1
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背景
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Protein Background: ADAR1 (Double-stranded RNA-specific adenosine deaminase), Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins since the translational machinery read the inosine as a guanosine, pre-mRNA splicing by altering splice site recognition sequences, RNA stability by changing sequences involved in nuclease recognition, genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication, and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing).
Short Description: Recombinant ADAR1 (1-295) protein that includes amino acids 1-295 of human ADAR1 protein (accession number NP_001102.3) was expressed in E. coli cells with an N-terminal 6xHis and Flag tag. The molecular weight of the protein is 35.88 kDa.
Aliases: DRADA, Double Stranded RNA -Specific Adenosine Deaminase, G1P1, IFI4, Interferon Inducible Protein 4, DSRAD, IFI-4, P136, DSH
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途径
- Protein targeting to Nucleus
抗原
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