YWHAB 蛋白
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北京 101111
Quick Overview for YWHAB 蛋白 (ABIN7938556)
抗原
See all YWHAB 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant YWHAB protein
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想要此Protein的其他选项吗?
!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant YWHAB protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- YWHAB (14-3-3 alpha + beta (YWHAB))
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别名
- YWHAB
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背景
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Protein Background: YWHAB (14-3-3 protein beta/alpha) is a member of the highly conserved 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Short Description: Recombinant YWHAB protein that includes full length of human YWHAB protein (accession number NP_003395.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 30.25 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: KCIP-1, 14-3-3 protein beta/alpha, protein 1054, GW128
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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