LTA Protein (His tag)
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北京 101111
Quick Overview for LTA Protein (His tag) (ABIN7884536)
抗原
See all LTA 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- This LTA protein is labelled with His tag.
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原理
- TNF beta (Tumor necrosis factor beta), Mouse
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序列
- LSGVRFSAAR TAHPLPQKHL THGILKPAAH LVGYPSKQNS LLWRASTDRA FLRHGFSLSN NSLLIPTSGL YFVYSQVVFS GESCSPRAIP TPIYL AHEVQLFSSQ YPFHVPLLSA QKSVYPGLQG PWVRSMYQGA VFLLSKGDQL STHTDGISHL HFSPSSVFFG AFAL with polyhistid ine tag at the N-terminus
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内毒素水平
- <0.1 EU per 1 μg protein
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Biological Activity Comment
- ED50 <30 ng/mL
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- dissolve in sterile H2O
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缓冲液
- PBS, pH 8.0
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储存条件
- -20 °C
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储存方法
- -20°C
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- LTA (Lymphotoxin-alpha (LTA))
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别名
- TNF beta
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背景
- TNF-β works as a potential mediator in the inflammatory and immune process. It a component of the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is secreted by activated T and B lymphocytes, and has similar function to TNF-α. In the same manner as TNF-α, TNF-β is involved in the regulation of various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is generally released as a soluble polypeptide. In addition, lymphotoxin-β can anchor TNF-β to the cell surface and form heterotrimers in an effective manner. TNF-β is cytotoxic to a wide range of tumor cells.
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分子量
- 22kDa
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基因ID
- 16992
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NCBI登录号
- NP_034865
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UniProt
- P09225
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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