IL-31 Protein (His tag)
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Quick Overview for IL-31 Protein (His tag) (ABIN7884497)
抗原
See all IL-31 (IL31) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This IL-31 protein is labelled with His tag.
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原理
- IL-31 (Interleukin-31), Mouse
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序列
- MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCF NPLNLNISVP GNTDESYDCK VFVLTVLKQF SNCMAELQAK DNTTC with polyhistid ine tag at the Cterminus
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内毒素水平
- <0.1 EU per 1 μg protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- dissolve in sterile H2O
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- IL-31 (IL31) (Interleukin 31 (IL31))
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别名
- IL-31
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背景
- Interleukin-31 (IL-31) s an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. It is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
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分子量
- 18kDa
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基因ID
- 76399
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NCBI登录号
- NP_083870
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UniProt
- Q6EAL8
抗原
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