IL-4 蛋白
Our Local Distributor
北京 101111
Quick Overview for IL-4 蛋白 (ABIN7866469)
抗原
See all IL-4 (IL4) 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
原理
- Recombinant Mouse IL-4 Protein
-
序列
- MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
-
特异性
- Chromosomal location:11 B1.3, 11 29.0 cM
-
产品特性
- Length (aa):120
-
内毒素水平
- < 0.1 ng/μg of protein (< 1EU/μg)
-
-
-
-
应用备注
- The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
-
限制
- 仅限研究用
-
-
-
- IL-4 (IL4) (Interleukin 4 (IL4))
-
别名
- IL-4
-
背景
-
Synonyms: Il4, Il-4, BSF-1
Description: Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
-
分子量
- 13.5 kDa
-
基因ID
- 16189
-
NCBI登录号
- NM_021283, NP_067258
-
UniProt
- P07750
-
途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
抗原
-