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IL-2 蛋白

This Recombinant IL-2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7866432
发货至: 中国
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Quick Overview for IL-2 蛋白 (ABIN7866432)

抗原

See all IL-2 (IL2) 蛋白
IL-2 (IL2) (Interleukin 2 (IL2))

蛋白类型

Recombinant

生物活性

Active

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大肠杆菌(E. Coli)

纯度

> 98 % by SDS-PAGE
  • 原理

    Recombinant Human IL-2 Protein

    序列

    MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLHYKDPAA NKARKEAELA AATAEQ

    特异性

    Chromosomal location:4q26-q27

    产品特性

    Length (aa):156

    内毒素水平

    < 0.1 ng per μg of IL-2
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  • 应用备注

    The ED50 as determined by the dose-dependent stimulation of proliferation of murine D10G4.1 cells is in the range of 0.1-0.5 ng/mL.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    50 mM acetic acid,The lyophilized IL-2 should be reconstituted in 50 mM acetic acid to a concentration not less than 100 μg/mL. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.

    缓冲液

    50 mM acetic acid

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    0 °C,-20 °C

    储存方法

    The lyophilized IL-2, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted IL-2 should be stored in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    Synonyms: IL2, IL-2, TCGF, lymphokine

    Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 (modified at the C-terminal end) is a 15.5 kDa protein, containing 156 amino acid residues including one intrachain disulfide bond.

    分子量

    15.5 kDa

    基因ID

    3558

    NCBI登录号

    NM_000586, NP_000577

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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