IL-2 蛋白
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北京 101111
Quick Overview for IL-2 蛋白 (ABIN7866432)
抗原
See all IL-2 (IL2) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human IL-2 Protein
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序列
- MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLHYKDPAA NKARKEAELA AATAEQ
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特异性
- Chromosomal location:4q26-q27
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产品特性
- Length (aa):156
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内毒素水平
- < 0.1 ng per μg of IL-2
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应用备注
- The ED50 as determined by the dose-dependent stimulation of proliferation of murine D10G4.1 cells is in the range of 0.1-0.5 ng/mL.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 mM acetic acid,The lyophilized IL-2 should be reconstituted in 50 mM acetic acid to a concentration not less than 100 μg/mL. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.
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缓冲液
- 50 mM acetic acid
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- 0 °C,-20 °C
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储存方法
- The lyophilized IL-2, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted IL-2 should be stored in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles.
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- IL-2 (IL2) (Interleukin 2 (IL2))
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别名
- IL-2
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背景
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Synonyms: IL2, IL-2, TCGF, lymphokine
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 (modified at the C-terminal end) is a 15.5 kDa protein, containing 156 amino acid residues including one intrachain disulfide bond.
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分子量
- 15.5 kDa
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基因ID
- 3558
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NCBI登录号
- NM_000586, NP_000577
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UniProt
- P60568
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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