BMP2 蛋白
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北京 101111
Quick Overview for BMP2 蛋白 (ABIN7866430)
抗原
See all BMP2 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human BMP-2 Protein
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序列
- MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
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特异性
- Chromosomal location:20p12
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产品特性
- Length (aa):115
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内毒素水平
- < 0.1 ng per μg of BMP-2
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Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) (Active) protein
BMP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Bone Morphogenetic Protein 2 (BMP2) (AA 1-396) protein (GST tag)BMP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 231-330) protein (GST tag)BMP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (GST tag)BMP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (Fc Tag)BMP2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Bone Morphogenetic Protein 2 (BMP2) proteinBMP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) (Active) proteinBMP2 宿主: 人, 犬, 大鼠, 小鼠, 猕猴 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Bone Morphogenetic Protein 2 (BMP2) (AA 284-396) proteinBMP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >92 % as determined by SDS-PAGE.
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应用备注
- Measured by the ability of BMP-2 to induce alkaline phosphatase production by C2C12 myogenic cells. The ED50 for this effect is typically 0.3-0.8 μg/mL.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 mM acetic acid,The lyophilized BMP-2 is best soluble in 50 mM acetic acid at a concentration of 0.1 mg/mL but should be also soluble in most aqueous buffers when the pH is below 6.0.
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缓冲液
- 50 mM acetic acid
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
- Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted BMP-2 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles!
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有效期
- 6 months
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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别名
- BMP-2
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背景
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Synonyms: bone morphogenetic protein 2, BDA2, BMP2A, bone morphogenetic protein 4, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6
Description: Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. BMP-2 is a heparin binding protein.
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分子量
- 26.0 kDa
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基因ID
- 650
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NCBI登录号
- NM_001200, NP_001191
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UniProt
- P12643
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
抗原
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