CXCL12 蛋白
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北京 101111
Quick Overview for CXCL12 蛋白 (ABIN7866195)
抗原
See all CXCL12 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- SDF1 – Stromal Cell-Derived Factor 1α ( CXCL12) tested in migration, LPS-Free
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序列
- CXCL12 consists of 69 amino acid residues: MKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK
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产品特性
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Recombinant Stromal Cell-Derived Factor 1α (SDF-1alpha) is a 8 kDa chemokine protein expressed in many tissues and cell types. The protein is almost identical (92% homology) in human, mouse and rat.
The chemokine SDF-1α binds to the chemokine receptor CXCR4 and plays an essential and unique role in homeostatic regulation of leukocyte traffic, hematopoiesis, organogenesis, cell differentiation and tissue regeneration (Murphy, 2002).
SDF-1alpha forms an heterocomplex with the alarmin HMGB1 (High Mobility Group 1) to promote the recruitment of cells via CXCR4 receptor. -
纯化方法
- Purified
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内毒素水平
- LPS-free: Pierce™ Chromogenic Endotoxin Quant Kit, <0.1 EU/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- The lyophilized protein once reconstituted with distilled water will be dissolved in a solution of DPBS without Ca and Mg.
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缓冲液
- The product contains contains < 0.006% v/v of Triton X-114 due to LPS removal. Remaining traces can be removed upon request.
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储存条件
- 4 °C/-20 °C
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储存方法
- 2-8°C when lyophilized. The protein once reconstituted with water can be stored frozen (-20°C). Avoid repeated freezing and thawing.
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- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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别名
- SDF1 alpha
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分子量
- 8 kDa
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
抗原
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