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IL-13 蛋白

This Recombinant IL-13 protein is expressed in 人细胞.
产品编号 ABIN7849723
发货至: 中国
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Quick Overview for IL-13 蛋白 (ABIN7849723)

抗原

See all IL-13 (IL13) 蛋白
IL-13 (IL13) (Interleukin 13 (IL13))

蛋白类型

Recombinant

宿主

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资源

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人细胞

应用范围

SDS-PAGE (SDS)

纯度

>95 % by SDS-PAGE
  • 原理

    Recombinant Human IL-13 Protein

    过滤

    0.2 μm filtered

    内毒素水平

    <0.01 EU/μg by LAL test
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    IL-13

    背景

    Synonyms: IL13, IL-13, P600, interleukin 13

    Description: Recombinant human IL-13 is produced by the mammalian system, with the target gene encoding Gly35-Asn146 expressed with 6x His-tag at the C-terminus.

    Background: Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene.IL-13 was first cloned in 1993 and is located on chromosome 5q31.1 with a length of 1.4kb.It has a mass of 13 kDa and folds into 4 alpha helical bundles.The secondary structural features of IL-13 are similar to that of Interleukin 4 (IL-4), however it only has 25 % sequence identity to IL-4 and is capable of IL-4 independent signaling.IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes.Interleukin-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis and chitinase up-regulation.It is a mediator of allergic inflammation and different diseases including asthma,and atopic dermatitis.

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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