ACVA 蛋白
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北京 101111
Quick Overview for ACVA 蛋白 (ABIN7849716)
抗原
See all ACVA 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human / Mouse/ Rat Activin A Protein
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过滤
- 0.2 μm filtered
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内毒素水平
- <0.01EU/μg by LAL test
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl,4 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- ACVA (Activin A (ACVA))
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别名
- Activin A
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背景
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Synonyms: Activin beta A chain,EDF,FRP,INHBA,Inhibin Beta A,Inhibin beta A chain,Inhibin β-A,inhibin,beta A
Description: Recombinant human Activin A is produced by the mammalian system, with the target gene encoding Gly311-Ser426 expressed.
Background: Activin A is a homodimer of 14 kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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UniProt
- P08476
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途径
- Hormone Transport, Peptide Hormone Metabolism
抗原
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