CNTF 蛋白
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北京 101111
Quick Overview for CNTF 蛋白 (ABIN7849711)
抗原
See all CNTF 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human CNTF Protein
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过滤
- 0.2 μm filtered
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内毒素水平
- <1 EU/μg by LAL test
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 6 % Sucrose, 4 % Mannitol, 0.05 % Tween 80, pH 8.0.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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别名
- CNTF
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背景
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Synonyms: CNTF, Hciliary neurotrophic factor
Description: Recombinant human CNTF is produced by the E.coli system, with the target gene encoding Ala2-Met200 expressed.
Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. It is a hypothalamic neuropeptide that is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also cotranscribed with the upstream ZFP91 gene.
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UniProt
- P26441
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途径
- JAK/STAT Signaling
抗原
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