MMP2 蛋白
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北京 101111
Quick Overview for MMP2 蛋白 (ABIN7849707)
抗原
See all MMP2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human MMP-2 Protein
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过滤
- 0.2 μm filtered
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内毒素水平
- <1 EU/μg by LAL test
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP-2
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背景
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Synonyms: 72 kDa Type IV Collagenase, 72 kDa Gelatinase, Gelatinase A, Matrix Metalloproteinase-2, MMP-2, TBE-1, MMP2, CLG4A
Description: Recombinant human MMP-2 is produced by the mammalian system, with the target gene encoding Ala30-Cys660 expressed with 6x His-tag at the C-terminus.
Background: 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.The MMP2 gene is located on chromosome 16 at position 12.2.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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