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CKM 蛋白

This Recombinant CKM protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7849674
发货至: 中国
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Quick Overview for CKM 蛋白 (ABIN7849674)

抗原

See all CKM 蛋白
CKM (Creatine Kinase, Muscle (CKM))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

ELISA

纯度

>90 % by SDS-PAGE
  • 原理

    Recombinant Human Creatine kinase muscle,CK-MMprotein
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    20 mM Tris-HCl pH 8.0.

    储存条件

    4 °C,-20 °C

    储存方法

    Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
  • 抗原

    CKM (Creatine Kinase, Muscle (CKM))

    别名

    Creatine kinase muscle,CK-MM

    背景

    Synonyms: CKM, CKMM, creatine kinase M, Creatine kinase M type, creatine kinase muscle, creatine kinase muscle type, Creatine Kinase M-type, M-CK, MCK.

    Description: Recombinant creatine kinasemuscle type,CK-MM Protein.

    Background: Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.

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