Thyroperoxidase 蛋白
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北京 101111
Quick Overview for Thyroperoxidase 蛋白 (ABIN7849670)
抗原
See all Thyroperoxidase (TPO) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Thyroid peroxidase, TPOProtein
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Thyroid Peroxidase (TPO) (AA 32-834) (Active) protein (His tag)
TPO 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 19-846) (Active) protein (His tag)TPO 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 672-779) protein (GST tag)TPO 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) (AA 1-933) protein (GST tag)TPO 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) protein (His tag)TPO 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Thyroid Peroxidase (TPO) (Active) protein (His tag)GMP Grade TPO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % WB Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 20 mM Tris-HCl ( pH 8.0).
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- TPO
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背景
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Synonyms: Thyroid peroxidase, TPO, thyroperoxidase, iodide peroxidase
Description: Recombinant human TPO protein.
Background: Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. In humans, thyroperoxidase is encoded by the TPO gene. Thyroid peroxidase (TPO) deficiency, caused by biallelic TPO mutations, is a well-established genetic form of congenital hypothyroidism (CH). TPO mutations with residual activity are associated with mild TPO deficiency, which is clinically characterized by marked goiter, mild TSH elevation, high serum T3to T4Molar ratio, and high serum thyroglobulin levels.
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途径
- Thyroid Hormone Synthesis
抗原
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