PLA2G7 蛋白
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北京 101111
Quick Overview for PLA2G7 蛋白 (ABIN7849665)
抗原
See all PLA2G7 (Lp-PLA2) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Lipoprotein-associated phospholipase A2, Lp-PLA2 Protein
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Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-440) (Active) protein (His tag)
Lp-PLA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (GST tag)Lp-PLA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 47-441) protein (His tag)Lp-PLA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (His-IF2DI Tag)Lp-PLA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) protein (His tag)Lp-PLA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Tris-Hcl, pH 10.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
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别名
- Lp-PLA2
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背景
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Synonyms: PLA2G7, LDL-PLA2, LP-PLA2, PAFAD, PAFAH, PAF-AH, Lipoprotein-associated phospholipase A2, phospholipase A2 group VII, gVIIA-PLA2, PAF acetylhydrolase
Description: Recombinant human LpPLA2 protein with his tag with molecular weight of 65.6 kDa.
Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Both LpPLA2 mass and activity were found within low-density lipoprotein (LDL) and HDL pools with more LpPLA2 mass being associated with HDL (54 % vs 44 %, P-value <.001) and more LpPLA2 activity being associated with LDL (56 % vs 40 %, P value = .02). In T1D, more LpPLA2 activity was associated with large- or less-dense LDL compared to those without diabetes. However, no difference in LpPLA2 activity or mass between lipoprotein subfractions was observed between all groups, and there was no relationship between LpPLA2 activity or mass and its distribution and CAC score progression in healthy or T1D men.LpPLA2 is found in both LDL and HDL and is distributed differently in men with T1D without any relationship to CAC score progression.
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途径
- Peptide Hormone Metabolism
抗原
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