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MUC1 蛋白

This Native MUC1 protein is expressed in Human.
产品编号 ABIN7849659
发货至: 中国
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Quick Overview for MUC1 蛋白 (ABIN7849659)

抗原

See all MUC1 蛋白
MUC1 (Mucin 1 (MUC1))

蛋白类型

Native

宿主

  • 26
  • 6
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  • 3

资源

  • 20
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Human

应用范围

SDS-PAGE (SDS)

纯度

>60 % by SDS-PAGE
  • 原理

    Native Human CA153 Protein
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM PBS, pH 7.4±0.2 with 0.2 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Ship at 4°C.Upon receipt, aliquot andstore at -20°C for long term. Avoid repeated freeze and thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CA153

    背景

    Synonyms: KL-6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, Breast carcinoma associated antigen DF3, CA15-3 antigen, CA15.3, Carcinoma associated mucin, CD 227, CD227, CD227 antigen, DF3 antigen, EMA, Episialin, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23AG, MAM6, MUC 1, MUC-1, Mucin 1, Mucin 1 precursor, Mucin1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated mucin

    Description: Purified human Cancer Antigen CA15-3 protein.

    Background: CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. It is derived from MUC1. CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased chance of early recurrence in breast cancer. Both CA 15-3 and CA 27-29 may be elevated in patients with benign ovarian cysts, benign breast disease, and benign liver disease. Elevations may also be seen in cirrhosis, sarcoidosis and lupus.

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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