AMH 蛋白
Our Local Distributor
北京 101111
Quick Overview for AMH 蛋白 (ABIN7849648)
抗原
See all AMH 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
原理
- Recombinant Human Muellerian-inhibiting substance/Anti-Muellerian hormone, MIS/AMH Protein
-
-
Anti-Mullerian Hormone (AMH) (AA 450-552) protein (His tag)
AMH 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Anti-Mullerian Hormone (AMH) protein (Myc-DYKDDDDK Tag)AMH 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.01 M PBS ( pH 7.4).
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- AMH (Anti-Mullerian Hormone (AMH))
-
别名
- MISAMH
-
背景
-
Synonyms: Muellerian-inhibiting factor, MIF, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS
Description: Recombinant human AMH protein from the region of N-terminal.
Background: Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH is a standard marker of ovarian reserve. Correlation between AMH and egg euploidy is controversial. Gat I et al study shows a correlation between AMH and aneuploidy rate, specifically among infertile patients younger than 37 years old. AMH is also a reliable marker of ovarian reserve in endometriosis patients, and it can predict follicular density in women undergoing ovarian tissue cryopreservation. In mammals, AMH prevents the development of the Müllerian ducts into the uterus and other Müllerian structures. The effect is ipsilateral, that is each testis suppresses Müllerian development only on its own side. In humans, this action takes place during the first 8 weeks of gestation. If no hormone is produced from the gonads, the Müllerian ducts automatically develop, while the Wolffian ducts, which are responsible for male reproductive parts, automatically die.
-
途径
- Negative Regulation of Hormone Secretion
抗原
-
