CLDN18.2 (AA 99-330) protein (Fc Tag)
This Recombinant CLDN18.2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7829768
发货至:
中国
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Quick Overview for CLDN18.2 (AA 99-330) protein (Fc Tag) (ABIN7829768)
抗原
CLDN18.2
蛋白类型
Recombinant
宿主
Cynomolgus
资源
HEK-293 Cells
应用范围
Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)
纯度
The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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产品特性
- AA 99-330
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标记
- Fc Tag
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原理
- Recombinant Cynomolgus CLDN18.2 protein with N-terminal human Fc tag
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特异性
- HFc(Glu99-Ala330) CLDN18.2(Asp28-Gln77)
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产品特性
- Extracellular Domain Protein
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CLDN18.2 protein (DYKDDDDK Tag)
宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc cryo-EM, ELISA, Imm, PhD, SPR
CLDN18.2 protein-VLP (DYKDDDDK Tag)宿主: 人 宿主: HEK-293 Cells VLP
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CLDN18.2
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背景
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SFTA5, SFTPJ
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] -
分子量
- predicted molecular mass of 31.9 kDa after removal of the signal peptide.
抗原
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