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CD38 Protein (AA 44-301) (His tag)

This Recombinant CD38 protein is expressed in HEK-293 Cells.
产品编号 ABIN7829742
发货至: 中国
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Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN7829742)

抗原

See all CD38 蛋白
CD38

蛋白类型

Recombinant

宿主

  • 23
  • 11
  • 6
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  • 1
Cynomolgus

资源

  • 15
  • 10
  • 7
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  • 2
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HEK-293 Cells

应用范围

Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

纯度

The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 44-301

    标记

    This CD38 protein is labelled with His tag.

    原理

    Recombinant Cynomolgus CD38 protein with N-terminal 10xHis tag

    特异性

    10xHis tag Cynomolgus CD38(Leu44-Ile301)

    产品特性

    Extracellular Domain Protein
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  • 应用备注

    Extracellular Domain Proteins (ECD) can be used as:
    • Immunogens for antibody drug development
    • Reagents used for CAR-T positive cell monitoring
    • Reagents for antibody screening and functional testing
    • Reagents for antibody affinity measurement

    说明

    The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please see Certificate of Analysis for specific instructions of reconstitution.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD38

    背景

    ADPRC1, cADPR1, ADPRC 1
    The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

    分子量

    predicted molecular mass of 31.2 kDa after removal of the signal peptide.

    UniProt

    Q5VAN0
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