VEGF (Aflibercept Biosimilar) Protein (Fc Tag)
This Recombinant VEGF (Aflibercept Biosimilar) protein is expressed in CHO Cells.
产品编号 ABIN7795087
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for VEGF (Aflibercept Biosimilar) Protein (Fc Tag) (ABIN7795087)
抗原
VEGF (Aflibercept Biosimilar)
蛋白类型
Recombinant
宿主
人
资源
CHO Cells
应用范围
In vivo Studies (in vivo)
纯度
>95% by SDS-PAGE under reducing conditions and HPLC
质量等级
Research Grade
-
-
标记
- This VEGF (Aflibercept Biosimilar) protein is labelled with Fc Tag.
-
原理
- Recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (hIgG1).
-
特异性
- The aflibercept biosimilar protein specifically binds to the human VEGF.
-
产品特性
- Research grade Aflibercept biosimilar has the same amino acid sequence as Aflibercept (trade name Eylea), a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (IgG1). It inhibits vascular endothelial growth factor (VEGF), and is used in the treatment of macular edema following Central Retinal Vein Occlusion (CRVO) and neovascular Age-Related Macular Degeneration (AMD). Aflibercept is a dimeric glycoprotein with a molecular weight of 96.9 kilo Daltons (kDa). Glycosylation adds its molecular weight to 115 kDa in total. Ziv-aflibercept (trade name Zaltrap) was developed as an injection for treatment of metastatic colorectal cancer.
-
纯化方法
- The aflibercept biosimilar protein was produced in CHO stable cell line.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
-
-
-
-
应用备注
- Functional assays, and those assays for studying biological pathways affected by aflibercept.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- pH 6.1, no stabilizers or preservatives
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
-
有效期
- 12 months
-
-
- VEGF (Aflibercept Biosimilar)
-
别名
- Aflibercept Biosimilar
-
物质类
- Biosimilar
抗原
-
You are here:
