S100A7A Protein (AA 1-108)
Quick Overview for S100A7A Protein (AA 1-108) (ABIN7669552)
抗原
See all S100A7A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 1-108
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原理
- Recombinant Mouse S100A15/S100A7A Protein
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序列
- Met1-Tyr108
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- S100A7A (S100 Calcium Binding Protein A7A (S100A7A))
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别名
- S100A15,S100A7A
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背景
- Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype. The association of the 11.2 kDa S100A7A / S100A15 with psoriasis suggests that it contributes to the pathogenesis of the disease and could provide a molecular target for therapy. ,Protein S100-A15A,Protein S100-A7A,S100 calcium-binding protein A15A,S100 calcium-binding protein A7A,S100a15a
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分子量
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calculated_mw: 12.9 kDa
observed_mw: 12 kDa
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UniProt
- Q6S5I3
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途径
- Activation of Innate immune Response, S100 Proteins
抗原
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