PODXL Protein (SUMO-His Tag)
Quick Overview for PODXL Protein (SUMO-His Tag) (ABIN7669448)
抗原
See all PODXL 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This PODXL protein is labelled with SUMO-His Tag.
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原理
- Recombinant Human PODXL protein (SUMO,His tag)
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序列
- Ala 220-Ile 431
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- PODXL
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背景
- Podocalyxin (PODXL), also known as Podocalyxin-like protein 1 (PCLP-1), is a heavily glycosylated transmembrane sialoprotein in the CD34 and Endoglycan family.Podocalyxin is expressed on glomerular and vascular endothelial cells, neurons, hematopoietic, mesenchymal, and cardiac stem cells, and metastatic carcinoma and glioblastoma tumor cells. A soluble form of Podocalyxin can be released into the urine of women with pre-eclampsia. Podocalyxin promotes platelet activation, neurite outgrowth, branching, and synaptogenesis, homing of hematopoietic progenitor cells to the bone marrow and spleen, and engraftment of mesenchymal and cardiac stem cells into ischemic heart and kidney. Its interactions with L-Selectin and E-Selectin mediate the tethering of lymphocytes and metastatic tumor cells to the vascular endothelium.,PCLP,PCLP-1,PCLP1,PCLPGCTM-2 antigen,PCpodocalyxin,POD XL,PODXL,Podocalyxin,Podocalyxin-like protein 1,podocalyxin-like
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分子量
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calculated_mw: 34.2 kDa
observed_mw: 32 kDa
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UniProt
- O00592
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途径
- Tube Formation
抗原
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