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PODXL Protein (SUMO-His Tag)

This Recombinant PODXL protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7669448
发货至: 中国

Quick Overview for PODXL Protein (SUMO-His Tag) (ABIN7669448)

抗原

See all PODXL 蛋白
PODXL (Podocalyxin-Like (PODXL))

蛋白类型

Recombinant

生物活性

Inactive

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 %
  • 标记

    This PODXL protein is labelled with SUMO-His Tag.

    原理

    Recombinant Human PODXL protein (SUMO,His tag)

    序列

    Ala 220-Ile 431

    纯化方法

    > 95 % as determined by reducing SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    < 10 EU/mg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    PODXL (Podocalyxin-Like (PODXL))

    别名

    PODXL

    背景

    Podocalyxin (PODXL), also known as Podocalyxin-like protein 1 (PCLP-1), is a heavily glycosylated transmembrane sialoprotein in the CD34 and Endoglycan family.Podocalyxin is expressed on glomerular and vascular endothelial cells, neurons, hematopoietic, mesenchymal, and cardiac stem cells, and metastatic carcinoma and glioblastoma tumor cells. A soluble form of Podocalyxin can be released into the urine of women with pre-eclampsia. Podocalyxin promotes platelet activation, neurite outgrowth, branching, and synaptogenesis, homing of hematopoietic progenitor cells to the bone marrow and spleen, and engraftment of mesenchymal and cardiac stem cells into ischemic heart and kidney. Its interactions with L-Selectin and E-Selectin mediate the tethering of lymphocytes and metastatic tumor cells to the vascular endothelium.,PCLP,PCLP-1,PCLP1,PCLPGCTM-2 antigen,PCpodocalyxin,POD XL,PODXL,Podocalyxin,Podocalyxin-like protein 1,podocalyxin-like

    分子量

    calculated_mw: 34.2 kDa

    observed_mw: 32 kDa

    UniProt

    O00592

    途径

    Tube Formation
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