Nectin-4 (NECTIN4) (Inactive) protein (His tag)
This Recombinant protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for Nectin-4 (NECTIN4) (Inactive) protein (His tag) (ABIN7669348)
抗原
Nectin-4 (NECTIN4)
蛋白类型
Recombinant
生物活性
Inactive
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 %
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标记
- His tag
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原理
- Recombinant Human Nectin-4/NECTIN4 protein (His tag)
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序列
- Gly 32-Leu 146
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Nectin-4 (NECTIN4)
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别名
- Nectin-4,NECTIN4
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背景
- Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and-heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.,Ig superfamily receptor LNIR,LNIR,Nectin-4,PRR4,PVRL4,Poliovirus receptor-related protein 4
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分子量
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calculated_mw: 12.5 kDa
observed_mw: 15 kDa
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UniProt
- Q96NY8
抗原
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