IL17D Protein (His tag)
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Quick Overview for IL17D Protein (His tag) (ABIN7669044)
抗原
See all IL17D 蛋白蛋白类型
宿主
资源
纯度
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标记
- This IL17D protein is labelled with His tag.
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原理
- Recombinant Mouse IL-17D protein(N-His)
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序列
- Ala 25-Arg 205
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纯化方法
- > 98 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL17D (Interleukin 17D (IL17D))
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别名
- IL-17D
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背景
- UNQ,IL 27,IL-27,IL 17D,IL 22,IL-17D,IL27,Interleukin 17D,Interleukin 27,Interleukin-17D,Interleukin-27,IL17D,UNQ3096,PRO21175,The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27 % aa sequence homology. IL-17D is expressed preferentially in skeletal muscle, heart, adipose tissue, lung, pancreas, and nervous system. Like other IL-17 family members, IL-17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines including IL-6, IL-8, and GM-CSF. IL-17D has also been shown to suppress the proliferation of myeloid progenitors in colony formation assays.
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分子量
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Calculated MW: 20.7 kDa
Observed MW: 25 kDa
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UniProt
- A0A0B4J1G4
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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