IgG4 Protein (AA 99-327) (His tag)
This Recombinant IgG4 protein is expressed in HEK-293 Cells.
产品编号 ABIN7668933
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for IgG4 Protein (AA 99-327) (His tag) (ABIN7668933)
抗原
IgG4
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Immunogen (Imm)
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 99-327
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标记
- This IgG4 protein is labelled with His tag.
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原理
- Recombinant Human IgG4-Fc Protein (His Tag)
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序列
- Glu99-Lys327
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IgG4
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物质类
- Antibody
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背景
- IGHG4,Ig gamma-4 chain C region,IgG4 Fc,SCN3B (sodium channel, voltage-gated, type III, beta,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.
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分子量
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Calculated MW: 25.1 kDa
Observed MW: 35 kDa
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UniProt
- P01861
抗原
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