IFN omega (Active) protein (His tag)
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Quick Overview for IFN omega (Active) protein (His tag) (ABIN7668916)
抗原
蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- His tag
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原理
- Recombinant Human IFN omega protein(His Tag)
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序列
- Cys 24-Ser 195
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过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measure by its ability to induce cytotoxicity in TF-1 cells. The ED50 for this effect is <0.02 ng/mL. The specific activity of recombinant human IFN omega is approximately >5 x107 IU/ mg.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IFN omega
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背景
- Interferon omega-1 is also known as Interferon alpha-II-1and IFNW1. It is a Secreted protein that in humans is encoded by the IFNW1 gene. IFNW1 belongs to the alpha/beta interferon family. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. IFNW1 is a recently discovered protein structurally related to IFN-alpha and -beta. It has been shown that IFN-omega 1 similar to that of other human class I IFNs, potent antiviral activity was also observed on cells of bovine and ovine but not of equine or murine origin.,IFN alpha II-1,IFNW1
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分子量
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calculated_mw: 20.9 kDa
observed_mw: 20 kDa
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UniProt
- P05000
抗原
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