Hepcidin Protein (AA 59-83) (His-TRX)
Quick Overview for Hepcidin Protein (AA 59-83) (His-TRX) (ABIN7668892)
抗原
See all Hepcidin (HAMP) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 59-83
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标记
- This Hepcidin protein is labelled with His-TRX.
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原理
- Recombinant Mouse Hepcidin/Hepc protein (TRX,His tag)
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序列
- Asp59-Thr83
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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别名
- Hepcidin,Hepc
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背景
- Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.,HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1,Hepcidin
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分子量
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calculated_mw: 22.6 kDa
observed_mw: 25 kDa
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UniProt
- Q9EQ21
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途径
- Hormone Activity, Transition Metal Ion Homeostasis
抗原
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