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Cofilin 2 Protein (CFL2) (His tag)

This Recombinant Cofilin 2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7668552
发货至: 中国
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Quick Overview for Cofilin 2 Protein (CFL2) (His tag) (ABIN7668552)

抗原

See all Cofilin 2 (CFL2) 蛋白
Cofilin 2 (CFL2)

蛋白类型

Recombinant

宿主

  • 13
  • 1
  • 1
  • 1

资源

  • 8
  • 3
  • 2
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 98 % as determined by reducing SDS-PAGE.
  • 标记

    This Cofilin 2 protein is labelled with His tag.

    原理

    Recombinant Human CFL2/cofilin 2/ADF Protein (His Tag)

    序列

    Ala 2-Leu 166

    纯化方法

    > 98 % as determined by reducing SDS-PAGE.

    过滤

    0.2 μm filtered

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.5
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Cofilin 2 (CFL2)

    别名

    CFL2

    背景

    NEM7,Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH -dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.

    分子量

    Calculated MW: 20.4 kDa

    Observed MW: 21 kDa

    基因ID

    1073

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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