CMV Glycoprotein B (CMV gB) (Inactive) 蛋白
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Quick Overview for CMV Glycoprotein B (CMV gB) (Inactive) 蛋白 (ABIN7668548)
抗原
蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein
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序列
- Arg 777-Val 907
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纯化方法
- > 90 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile Tris 50 mM, NaCl 100 mM, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CMV Glycoprotein B (CMV gB)
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别名
- cytomegalovirus (HCMV) Glycoprotein B
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物质类
- Viral Protein
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背景
- Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.,Glycoprotein B,gB
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分子量
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calculated_mw: 92.0 kDa
observed_mw: 130-140 kDa
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UniProt
- P13201
抗原
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