CD47 Protein (CD47) (His tag)
Quick Overview for CD47 Protein (CD47) (His tag) (ABIN7668379)
抗原
See all CD47 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
标记
- This CD47 protein is labelled with His tag.
-
原理
- Recombinant Mouse CD47 protein (His tag)
-
序列
- Gln 19-Lys 140
-
纯化方法
- > 95 % as determined by reducing SDS-PAGE.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
-
-
CD47 (CD47) (AA 19-141) protein (His tag)
CD47 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD47 (CD47) (AA 19-139) protein (His-Avi Tag,Biotin)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD47 (CD47) (AA 19-141) protein (mFc-His Tag)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD47 (CD47) (AA 19-140) protein (His tag)CD47 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD47 (CD47) (AA 19-139) (Active) protein (Fc Tag)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) (AA 19-139) (Active) protein (His tag)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) (AA 19-139) (Active) protein (Fc Tag,AVI tag,Biotin)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) proteinCD47 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
CD47 (CD47) (AA 19-139) (Active) protein (His tag,AVI tag)CD47 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
CD47 (CD47) (AA 19-141) (Active) protein (His tag)CD47 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
-
缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
有效期
- 12 months
-
-
- CD47
-
别名
- CD47
-
背景
- CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig-like domain, five membrane-spanning regions with short intervening loops, and C-terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.,Antigenic Surface Determinant Protein OA3,CD47,Integrin-Associated Protein,LAP,Leukocyte Surface Antigen CD47,MER6,OA3,Protein MER6
-
分子量
-
calculated_mw: 13.3 kDa
observed_mw: 15 kDa
-
UniProt
- Q61735
抗原
-
