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CD47 Protein (CD47) (His tag)

This Recombinant CD47 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7668378
发货至: 中国

Quick Overview for CD47 Protein (CD47) (His tag) (ABIN7668378)

抗原

See all CD47 蛋白
CD47

蛋白类型

Recombinant

生物活性

Inactive

宿主

  • 37
  • 15
  • 7
  • 6
  • 4
  • 2
  • 1
大鼠

资源

  • 42
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

> 95 %
  • 标记

    This CD47 protein is labelled with His tag.

    原理

    Recombinant Rat CD47 protein (His tag)

    序列

    Gln 19-Lys 140

    纯化方法

    > 95 % as determined by reducing SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    < 10 EU/mg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD47

    别名

    CD47

    背景

    CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.,CD47,Leukocyte surface antigen CD47

    分子量

    calculated_mw: 13.3 kDa

    observed_mw: 15 kDa

    UniProt

    P97829
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