Annexin a1 Protein (AA 2-346) (His tag)
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Quick Overview for Annexin a1 Protein (AA 2-346) (His tag) (ABIN7668176)
抗原
See all Annexin a1 (ANXA1) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 2-346
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标记
- This Annexin a1 protein is labelled with His tag.
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原理
- Recombinant Human Annexin A1/ANXA1 Protein
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序列
- Ala2-Asn346
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1,ANXA1
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背景
- Annexin A1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 Inhibitory Protein,p35,Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97 % of samples from patients with hairy cell leukemia.
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分子量
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Calculated MW: 38.6 kDa
Observed MW: 38 kDa
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基因ID
- 301
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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