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Albumin Protein (ALB)

This Recombinant Albumin protein is expressed in 酵母菌.
产品编号 ABIN7668136
发货至: 中国

Quick Overview for Albumin Protein (ALB) (ABIN7668136)

抗原

See all Albumin (ALB) 蛋白
Albumin (ALB)

蛋白类型

Recombinant

生物活性

Inactive

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酵母菌

纯度

> 95 %
  • 原理

    Recombinant Human Serum Albumin/HSA Protein

    序列

    Met 1-Leu609, Ala215Val,natrual variant

    纯化方法

    > 95 % as determined by reducing SDS-PAGE.

    过滤

    0.2 μm filtered
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Albumin (ALB)

    别名

    Serum Albumin

    背景

    Alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is an abundant protein of the plasma of vertebrates and members of several invertebrate phyla and functions as a broad-spectrum protease-binding protein. alpha-2-macroglobulin is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. alpha-2-macroglobulin is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it has been reported that numerous growth factors, cytokines and hormones bind to alpha 2M through diverse mechanisms. A2M is also produced in the brain where it binds multiple extracellular ligands and is internalized by neurons and astrocytes. In the brain of Alzheimer's disease (AD) patients, A2M has been localized to diffuse amyloid plaques. A2M also binds soluble beta-amyloid, of which it mediates degradation. Protease-conjugated alpha2-macroglobulin is selectively bound by cells contacting the body fluids and alpha2-macroglobulin and its protease cargo are then internalized and degraded in secondary lysosomes of those cells. In addition to this function as an agent for protease clearance, alpha2-macroglobulin binds a variety of other ligands, including several peptide growth factors and modulates the activity of a lectin-dependent cytolytic pathway in arthropods.,ALB;HAS;Serum Albumin

    分子量

    calculated_mw: 66.5 kDa

    observed_mw: 58-67 kDa

    UniProt

    P02768

    途径

    Lipid Metabolism
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