ACVA 蛋白
Quick Overview for ACVA 蛋白 (ABIN7668105)
抗原
See all ACVA 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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原理
- Recombinant Human/Mouse/Rat Activin A protein(His Tag)
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序列
- Gly 311-Ser 426
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过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED50 for this effect is <10 ng/mL. The specific activity of recombinant human Activin A is approximately >1.0 x 103 IU/mg.
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Activin A (ACVA) (AA 311-426) (Active) protein
ACVA 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Activin A (ACVA) (AA 21-426) (Active) protein (His tag)ACVA 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, Imm, SDS, ELISA, AcA Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- ACVA (Activin A (ACVA))
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别名
- Activin A
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背景
- Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.,Activin A,INHBA,Inhibin beta A chain
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分子量
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calculated_mw: 13.1 kDa
observed_mw: 15 kDa
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UniProt
- P08476
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途径
- Hormone Transport, Peptide Hormone Metabolism
抗原
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