YWHAB 蛋白
Quick Overview for YWHAB 蛋白 (ABIN7668089)
抗原
See all YWHAB 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human 14-3-3 beta/YWHAB Protein
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序列
- Met 1-Asn 246
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纯化方法
- > 93 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His tag)
custom-made YWHAB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His tag)custom-made YWHAB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His-IF2DI Tag)YWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (GST tag)YWHAB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His tag)YWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% by SDS-PAGE SDS
14-3-3 alpha + beta (YWHAB) (AA 1-246) proteinYWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
14-3-3 alpha + beta (YWHAB) (AA 1-246), (full length) protein (GST tag)YWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 150 mM NaCl, 0.1 mM DTT, 10 % glycerol, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- YWHAB (14-3-3 alpha + beta (YWHAB))
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别名
- 14-3-3 beta
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背景
- 14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal transduction, apoptosis and cell cycle regulation. 14-3-3 proteins are mainly localized in the synapses and neuronal cytoplasm, and seven isoforms have been identified in mammals. This family of proteins was initially identified as adaptor proteins which bind to phosphoserine-containing motifs. Binding motifs and potential functions of 14-3-3 proteins are now recognized to have a wide range of functional relevance. 14-3-3 beta / YWHAB is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. 14-3-3 beta / YWHAB interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. 14-3-3 beta / YWHAB has also been implicated in the pathogenesis of small cell lung cancer. 14-3-3 beta / YWHAB binding negatively regulates RSK1 activity to maintain signal specificity and that association/dissociation of the 14-3-3beta-RSK1 complex is likely to be important for mitogen-mediated RSK1 activation.,GW128,HEL-S-1,HS1,KCIP-1,YWHAA
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分子量
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calculated_mw: 28.0 kDa
observed_mw: 28 kDa
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UniProt
- P31946
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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