APOE Protein (AA 19-317) (His tag)
Quick Overview for APOE Protein (AA 19-317) (His tag) (ABIN7597463)
抗原
See all APOE 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-317
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标记
- This APOE protein is labelled with His tag.
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原理
- Recombinant human APOE4 Protein with C-terminal 6xHis tag
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序列
- APOE4(C130R)(Lys19-His317) 6xHis tag
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Apolipoprotein E (APOE) (AA 19-311) protein (Fc Tag)
APOE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein E (APOE) (AA 19-317) protein (Fc Tag)APOE 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Apolipoprotein E (APOE) (AA 19-311) protein (His tag)APOE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Apolipoprotein E (APOE) (AA 19-311) protein (His tag)APOE 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apolipoprotein E (APOE) protein (Myc-DYKDDDDK Tag)APOE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- APOE (Apolipoprotein E (APOE))
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别名
- APOE4
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背景
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APOE4
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] -
分子量
- predicted molecular mass of 35.1 kDa after removal of the signal peptide.
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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