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DKK3 Protein (AA 22-350) (Fc Tag)

宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597408
发货至: 中国
  • 抗原 See all DKK3 products
    DKK3
    蛋白类型
    Recombinant
    产品特性
    AA 22-350
    宿主
    • 12
    • 4
    • 1
    • 1
    资源
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DKK3 protein is labelled with Fc Tag.
    原理
    Recombinant human DKK3 Protein with C-terminal human Fc tag
    序列
    DKK3(Ala22-Ile350) hFc(Glu99-Ala330)
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 应用备注
    Extracellular Domain Proteins (ECD) can be used as:
    • Immunogens for antibody drug development
    • Reagents used for CAR-T positive cell monitoring
    • Reagents for antibody screening and functional testing
    • Reagents for antibody affinity measurement
    说明

    The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    DKK3
    Abstract
    DKK3 产品
    背景
    RIG, CRRL, REIC
    This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
    分子量
    predicted molecular mass of 62.4 kDa after removal of the signal peptide. The apparent molecular mass of DKK3-hFc is 70-130 kDa due to glycosylation.
    UniProt
    Q9UBP4
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