TLR5 蛋白
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北京 101111
Quick Overview for TLR5 蛋白 (ABIN7597223)
抗原
See all TLR5 蛋白蛋白类型
宿主
资源
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原理
- Human TLR5 full length protein-MNP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- TLR5 (Toll-Like Receptor 5 (TLR5))
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别名
- TLR5
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背景
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MELIOS, SLE1, SLEB1, TIL3
Toll-like receptor (TLR) family plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease. -
分子量
- The human full length TLR5 protein has a MW of 97.8 kDa
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UniProt
- O60602
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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