STING1 protein (DYKDDDDK Tag,Strep Tag)
This Synthetic Nanodisc protein is expressed in HEK-293 Cells.
Quick Overview for STING1 protein (DYKDDDDK Tag,Strep Tag) (ABIN7596525)
抗原
STING1
蛋白类型
Synthetic Nanodisc
宿主
人
资源
HEK-293 Cells
应用范围
Cryogenic electron microscopy (cryo-EM), ELISA, Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
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标记
- DYKDDDDK Tag,Strep Tag
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原理
- Human STING1-Strep full length protein-synthetic nanodisc
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STING1 protein
宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
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说明
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- STING1
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背景
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ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
A five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. -
分子量
- The human full length STING1-Strep protein has a MW of 42.2 kDa
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UniProt
- Q86WV6
抗原
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