SREBF chaperone Protein (SCAP) (DYKDDDDK Tag)
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- 抗原 See all SREBF chaperone (SCAP) 蛋白
- SREBF chaperone (SCAP)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SREBF chaperone protein is labelled with DYKDDDDK Tag.
- 应用范围
- ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- 原理
- Human SCAP full length protein-synthetic nanodisc
- Top Product
- Discover our top product SCAP 蛋白
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- 说明
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- SREBF chaperone (SCAP)
- 别名
- SCAP (SCAP 产品)
- 背景
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N/A
A protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. - 分子量
- The human full length SCAP protein has a MW of 139.7 kDa
- UniProt
- Q12770
- 途径
- SARS-CoV-2 Protein Interactome
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