DC-SIGN/CD209 Protein (AA 60-404) (hIgG-His-tag)
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- 抗原 See all DC-SIGN/CD209 (CD209) 蛋白
- DC-SIGN/CD209 (CD209) (CD209)
- 蛋白类型
- Recombinant
- 产品特性
- AA 60-404
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This DC-SIGN/CD209 protein is labelled with hIgG-His-tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
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VSKVPSS ISQEQSRQDA IYQNLTQLKA AVGELSEKSK LQEIYQELTQ LKAAVGELPE KSKLQEIYQE LTRLKAAVGE LPEKSKLQEI YQELTWLKAA VGELPEKSKM QEIYQELTRL KAAVGELPEK SKQQEIYQEL TRLKAAVGEL PEKSKQQEIY QELTRLKAAV GELPEKSKQQ EIYQELTQLK AAVERLCHPC PWEWTFFQGN CYFMSNSQRN WHDSITACKE VGAQLVVIKS AEEQNFLQLQ SSRSNRFTWM GLSDLNQEGT WQWVDGSPLL PSFKQYWNRG EPNNVGEEDC AEFSGNGWND DKCNLAKFWI CKKSAASCSR DEEQFLSPAP ATPNPPPA - 纯度
- > 90% by SDS - PAGE
- 内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD209 蛋白
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CD209 (CD209) (AA 59-404) protein (His tag)
CD209 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD209 (CD209) (AA 1-404) protein (His tag)custom-made CD209 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD209 (CD209) protein (Fc Tag)CD209 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
CD209 (CD209) (AA 1-404) protein (GST tag)CD209 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD209 (CD209) (AA 271-380) protein (GST tag)CD209 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- DC-SIGN/CD209 (CD209 产品)
- 背景
- DC-SIGN/CD209, also known as Dendritic Cell-specific ICAM-3 Grabbing Non-integrin, is a member of the C-type lectin family. It is Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. DC-SIGN on macrophages recognises and binds with high affinity to high-mannose type N-glycans, a class of pathogen associated molecular patterns PAMPs commonly found on viruses, bacteria and fungi. This binding interaction activates phagocytosis. It has a high affinity for the ICAM3 Molecule and binds various microorganisms by recognizing high-mannose-containing glycoproteins on their envelopes and especially functions as receptor for several viruses such as HIV and Hepatitis C. Besides functioning as an adhesion molecule, recent study has also shown that DC-SIGN can initiate innate immunity by modulating toll-like receptors, though the detailed mechanism is not yet known. It together with other C-type lectins is involved in recognition of tumors by dendritic cells. It is also a potential engineering target for dendritic cell based cancer vaccine. Recombinant human DC-SIGN/CD209, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 66.5kDa (587aa)
- NCBI登录号
- NP_066978
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